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Abstract CUPID, the CUORE Upgrade with Particle Identification, is a next-generation experiment to search for neutrinoless double beta decay ($$0\mathrm {\nu \beta \beta }$$ $0\nu \beta \beta$) and other rare events using enriched Li$$_{2}$$ $_2^{}$$$^{100}$$ $_{}^{100}$MoO$$_{4}$$ $_4^{}$scintillating bolometers. It will be hosted by the CUORE cryostat located at the Laboratori Nazionali del Gran Sasso in Italy. The main physics goal of CUPID is to search for$$0\mathrm {\nu \beta \beta }$$ $0\nu \beta \beta$of$$^{100}$$ $_{}^{100}$Mo with a discovery sensitivity covering the full neutrino mass regime in the inverted ordering scenario, as well as the portion of the normal ordering regime with lightest neutrino mass larger than 10 meV. With a conservative background index of 10$$^{-4}$$ $_{}^{-4}$ cts$$/($$ $/($keV$$\cdot $$ $·$kg$$\cdot $$ $·$yr$$)$$ $)$, 240 kg isotope mass, 5 keV FWHM energy resolution at 3 MeV and 10 live-years of data taking, CUPID will have a 90% C.L. half-life exclusion sensitivity of$$1.8\cdot 10^{27}$$ $1.8·{10}^{27}$ yr, corresponding to an effective Majorana neutrino mass ($$m_{\beta \beta }$$ $m_{\beta \beta }$) sensitivity of 9–15 meV, and a$$3\sigma $$ $3\sigma$discovery sensitivity of$$1\cdot 10^{27}$$ $1·{10}^{27}$ yr, corresponding to an$$m_{\beta \beta }$$ $m_{\beta \beta }$range of 12–21 meV. 

We present a search for long-lived particles (LLPs), produced in kaon decays, that decay to two muons inside the ICARUS neutrino detector. This channel would be a signal of hidden sector models that can address outstanding issues in particle physics such as the strong CP problem and the microphysical origin of dark matter. The search is performed with data collected in the Neutrinos at the Main Injector (NuMI) beam at Fermilab corresponding to $2.41\times {10}^{20}$protons-on-target. No new physics signal is observed, and we set world leading limits on heavy QCD axions, as well as for the Higgs portal scalar among dedicated searches. Limits are also presented in a model-independent way applicable to any new physics model predicting the process $K\to \pi +S(\to \mu \mu )$, for a LLP $S$. This result is the first search for new physics performed with the ICARUS detector at Fermilab. It paves the way for the future program of LLP searches at ICARUS. Published by the American Physical Society2025